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Life Sciences
Life scientists post their preprints on bioRxiv, and quantitative biology appears on arXiv too. This page shows the newest papers ReadSearch has read from both, from cell biology and genetics to neuroscience, ecology and immunology.
606 papers, from 31 August 2026 to 5 November 2026: 423 arXiv preprints, 128 bioRxiv preprints and 55 OpenAlex records.
Newest papers, page 5
STRUCTURAL PLASTICITY ALLOWS DOUBLECORTIN AND DRUG-STABILIZED MICROTUBULES TO ACCOMMODATE EACH OTHER
Microtubule architecture and dynamics are modulated by small molecules, but how these compounds alter lattice properties and interactions with cellular regulators remains incompletely understood.The mechanism of cysteine sensing by LRRC58
Cysteine is essential for life but toxic in excess.High-throughput, single-cell-encoded colony imaging reveals infection-linked heterogeneity
Phenotypic heterogeneity within bacterial populations shapes adaptation, antibiotic tolerance, and infection dynamics, yet colony-level quantification remains difficult at scale and on…Gene expression in Anolis sagrei suggests conservation of patterning mechanisms drives formation of two high acuity areas
As humans we enjoy high acuity color vision.The Test Used to Choose Between Pesticide Survival Models Tracks Lesion Persistence, Not Hazard Structure
Aquatic pesticide risk assessment predicts survival with toxicokinetic-toxicodynamic models that offer two hazard structures, cumulative or peak-based, which disagree about which exposure patterns…Pervasive chromothripsis drives pleural mesothelioma to impact gene function and patient survival
Pleural mesothelioma (PM) is a tumour type showing high structural complexity but the full spectrum of variants present and their impacts are poorly understood.GINsim 3.1: Qualitative modelling and dynamical analysis of logical regulatory networks
GINsim is a software for the definition and dynamical analysis of qualitative (Boolean and multi-valued) models of biological regulatory networks.Predicting protein structures at any folding stage from sequence
Protein structure prediction has largely focused on native conformations, leaving the continuum of unfolded states, folding intermediates, and native structures difficult to access.Curriculum unlearning in humans and neural networks
During learning, humans often benefit from curricula that teach simple rules before exceptions.Ablating Design Choices for Protein Ensemble Generators Across Structural Regimes
Generative models of protein conformational ensembles inherit much of their design from structure prediction for folded proteins.Empirical Bayes Flow Matching for Continuous Cryo-EM Heterogeneity
We address the problem of learning generative priors over high-dimensional latent variables from indirect, noisy observations, with a focus on continuous heterogeneity in cryo-electron microscopy…iGC: Antibody Optimization via Reinforcement Learning over a Learned Somatic Hypermutation Prior
Antibody affinity maturation is a natural optimization process in which B cells acquire mutations through somatic hypermutation (SHM), undergo selection for improved antigen binding, and iteratively…Redesigning the Eterna100 RNA design benchmark for the Vienna 2 folding engine
The rational design of RNA is becoming important for rapidly developing technologies in medicine and biochemistry, spurring development of numerous RNA secondary structure design algorithms and…JUMP Cell Painting chemical dataset: Morphological map of 115,796 compounds in human cells
Image-based profiling decodes complex cellular states for high-impact biological and therapeutic applications, yet a large, public reference dataset of chemical perturbations has been lacking.Active vision modulates early cortical stages of visual processing: Evidence from MEG and eye-tracking
Vision is fundamentally active.A predictive mechanochemical modeling framework for the deformation and remodeling of the nuclear lamina
Nuclear envelope (NE) deformation and rupture are common in cell spreading and migration in a variety of microenvironments and lead to marked changes in nucleocytoplasmic transport.Benchmarking DNA Foundation Models: Biological Blind Spots in Evo2 Variant-Effect Prediction
DNA foundation models such as Evo2 and DNABERT-2 show promise for variant-effect prediction (VEP), yet rigorous benchmarks assessing their ability to capture established biological constraints…New perspectives in assessing environmental risks for birds: a simple TKTD framework to link growth and reproduction energy budget to chemical stress
Assessing the risk of pesticides to birds requires models that can extrapolate laboratory data to realistic exposure scenarios.Common variation of cell abundances and gene expression in the human striatum
The cellular and molecular bases of inter-individual variation in the human brain are not yet understood, particularly beyond the neocortex.Temperature-dependent performance scales with maximum heat tolerance across ectotherms
Temperature fundamentally shapes ectotherm biology, from continuous changes in sublethal performance to acute functional failure at upper thermal limits.
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