A field on ReadSearch
Life Sciences
Life scientists post their preprints on bioRxiv, and quantitative biology appears on arXiv too. This page shows the newest papers ReadSearch has read from both, from cell biology and genetics to neuroscience, ecology and immunology.
606 papers, from 31 August 2026 to 5 November 2026: 423 arXiv preprints, 128 bioRxiv preprints and 55 OpenAlex records.
Newest papers, page 6
Learning complex temporal dependencies via local synaptic plasticity
The ability to extract and exploit temporal structure across diverse tasks is central to human cognition.Surprisal contributes little beyond contextual embeddings in high-gamma ECoG encoding
Surprisal and contextual embeddings are both derived from large language models and are widely used to predict neural responses during language comprehension, but it is unclear whether surprisal…Region-dependent regulation of Tau phosphorylation by Glycerophosphodiester Phosphodiesterase 2 in a mouse model of tauopathy
Hyperphosphorylation of Tau promotes its aggregation and neurofibrillary tangle (NFT) formation, contributing to neuronal dysfunction and neurodegeneration in diseases such as Alzheimer's Disease…Intensive pine plantation management shapes infectious agent communities in the generalist rodent Apodemus sylvaticus, with consequences for zoonotic hazard
Land use change is widely recognized as a major driver of emerging zoonotic diseases.Gain-of-function mutations in the RodZ juxtamembrane domain promote Rod system activity in Escherichia coli
The peptidoglycan (PG) cell wall protects bacteria from osmotic lysis and determines their shape.scRM: A single-cell foundation model trained on scRNA-seq reads
To our knowledge, scRM is the first single-cell foundation model trained on sequencing reads, demonstrating that raw data pretraining is not only feasible but competitive at a fraction of the…Multimodal characterization of putative pan-inhibitory viral constructs in macaque monkeys
Transgenic approaches and validated viral vector toolboxes have advanced our understanding of how inhibitory neurons shape cognition and motor control in mice and other rodents.Donor Aware Reanalysis of Neuronal Nuclei Supports STMN2 Depletion Associated with Nuclear TDP 43 loss in FTD and ALS
Nuclear TDP-43 depletion is a central pathological feature of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but donor-to-donor variation can obscure transcriptomic…PHASOR: An Open-Source Pipeline for Hidden Markov Model Analysis of Stimulus-Locked Retinal Multielectrode-Array Population Activity
Multielectrode-array recordings of the retina reveal neural population activity at cellular resolution, but relating recurring population states to stimulus timing and single-unit responses requires…Predicting cortical signal mixing in coarse-resolution fMRI: a forward-operator analysis of surface mapping and the conditional benefit of correction
Surface-based fMRI projection can mix signals from cortical locations that are close in the volume but distant along the folded cortical sheet.FastaGuard: FASTA preflight QC for modern bioinformatics pipelines
FastaGuard is a streaming, explainable FASTA preflight QC tool that validates assembly FASTA files, detects structural and composition red flags, and emits a versioned multi-format report with an…A comparison of two culture and three sequencing methods for detection of the urobiome
Standard urine culture (SUC), the clinical reference method, is optimized for fast-growing aerobes and misses much of the urinary microbiota.BioResearchBench: 50 Long Horizon Biological Research Tasks
AI models are used in biology research to study disease mechanisms, discover potential treatments, analyze experimental data, troubleshoot problems, and plan next steps.A Physics-Constrained Marcus-Theory Optimization Framework Restores Parameter Identifiability in Deep-Pocket Oncogenic Drug Kinetics: A KRAS G12C and STAT3 Case Study
More than 90% of drug candidates fail preclinically, partly because empirical dose-response models such as the Hill equation ignore microenvironmental effects inside the deep binding pockets of…Ark-ADMET: endpoint-specific selection of molecular representations and hyperparameters for gradient-boosted ADMET models under the Therapeutics Data Commons benchmark protocol
Typical submissions to the Therapeutics Data Commons (TDC) absorption, distribution, metabolism, excretion, and toxicity (ADMET) benchmark leaderboard apply a single architecture and a single…Multi-scale place fields provide a predictive basis for hierarchical control
Hippocampal place cells typically exhibit unimodal spatial selectivity in small enclosures, but express multiple, irregularly spaced fields in environments of naturalistic scale.Discovery of P1-P2 depeptidized boronic acid based Plasmodium falciparum SUB1 inhibitor
The Plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1) is an essential enzyme required for parasite egress from host red blood cells and represents a promising target for antimalarial…CNVision: a computational framework for functional interpretation of intragenic copy number variants
Background Intragenic copy number variants (CNVs), including exon-level deletions and duplications within a single gene, represent an important class of pathogenic genomic variation.Hierarchical Uncertainty Transformation During Multimodal Comprehension
Human communication requires combining information from different modalities even when each source is incomplete or ambiguous.Detecting deception in event narratives: the analysis of response latencies and error rates to unexpected questions.
Deception is a central phenomenon in the study of human behaviour, and in forensic and investigative contexts it assumes significance due to its potential consequences.
Get the few papers worth your time in Life Sciences every morning.
Choose your topics and ReadSearch reads the new papers in them each day, then brings you the few worth reading, each with its key finding in a sentence.