PubMed ·

Diffusely impaired myocardial perfusion in patients with suspected coronary artery disease: Clinical utility of relative perfusion.

Niklas Vartiainen, Antti-Pekka E Rissanen, Suvi Hartikainen, Svantte Halttunen, Aleksi J Leikas, Elina Kariniemi, Eero Strengell, Paavo-Ilari Kuikka, Juha E K Hartikainen and Tomi P Laitinen

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PubMed
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Read it at PubMed
Topics
Cardiology

In brief

Unlocking CAD Insights with Myocardial Blood Flow

This study introduces a novel approach using relative hyperaemic myocardial blood flow (MBF) to predict obstructive CAD. By analyzing data from 874 patients, the authors demonstrate that lower relative hyperaemic MBF is a strong indicator of obstructive disease.

What they found: The study found that 53% of patients with diffusely impaired hyperaemic MBF had obstructive CAD. The relative hyperaemic MBF was significantly lower in these patients, with values of 66% for obstructive versus 52% for non-obstructive CAD. The predictive accuracy of relative hyperaemic MBF was solid, with an area under the curve of 0.778.

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From the abstract

In patients with suspected coronary artery disease (CAD), diffusely impaired hyperaemic myocardial blood flow (MBF) may indicate a multivessel epicardial CAD but also impaired coronary microcirculation.

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