A field on ReadSearch
Life Sciences
Life scientists post their preprints on bioRxiv, and quantitative biology appears on arXiv too. This page shows the newest papers ReadSearch has read from both, from cell biology and genetics to neuroscience, ecology and immunology.
606 papers, from 31 August 2026 to 5 November 2026: 423 arXiv preprints, 128 bioRxiv preprints and 55 OpenAlex records.
Newest papers, page 3
Disease-Causing Mutations Alter the Interplay Between Loop Dynamics and Catalysis in the Protein Tyrosine Phosphatases SHP-1 and SHP-2
The protein tyrosine phosphatases (PTPs) SHP-1 and SHP-2 play complex roles in a variety of signaling pathways, including those involved in cancers and other diseases, making them important drug…How the Azadithiolate Ligand Impacts O2-Stability of Group B -Hydrogenase ToHydA
[FeFe]-hydrogenases are metalloenzymes that catalyze the reversible oxidation and production of H2, making them potential candidates for sustainable energy solutions.An endogenous retrovirus insertion disrupting bovine ALKBH8 causes a failure-to-thrive syndrome with immunodeficiency associated with juvenile mortality in Brown Swiss cattle
The Brown Swiss (BS) cattle breed is one of the major Swiss dairy breeds.Salt stress shifts wild tomato root systems toward transport efficiency along a gravitropism-constrained Pareto front
- Root system architecture balances the carbon cost of building roots (wiring cost) against transport speed to the shoot (conduction delay).Somatic genetic variation shapes clonal selection of memory NK cells
In adaptive immunity, antigen receptor specificity and affinity drive clonal selection, but what enables individual innate lymphocytes to gain a selective advantage without rearranged antigen…The transcription factor THAP11 is a general regulator of early embryonic polarization
During mouse embryogenesis, three sequential waves of cell polarization occur in the 8-cell-morula trophectoderm (TE), E3.5-E4.5 primitive endoderm (PrE), and E4.5-E5.5 epiblast (Epi), driving cell…Islet size, cellular composition, and spatial location are interconnected in the human pancreas
Stem cell-derived (SC) islets hold promise as a transformative therapy for type 1 diabetes (T1D).The AP-1 clathrin adaptor has a conserved role in recycling resident proteins of the trans-Golgi network
Although the AP-1 clathrin adaptor has been studied for decades, its role in membrane trafficking has been ambiguous.Serial dependence carries the action that produced the previous report
Serial dependence pulls current judgments toward the recent past, but what is carried forward is debated: the previous stimulus, the previous decision, or something about the report itself.Cellular composition and the interpretation of candidate RNA readouts of trogocytosis in colorectal cancer
RNA measurements of genes associated with trogocytosis may reflect cellular composition rather than contact-dependent membrane acquisition.NeuroWeave-3D: Uncertainty-Aware Evidence Completion for Brain Tumor Segmentation with Missing MRI Modalities
Multi-parametric MRI segmentation models are accurate when all prescribed sequences are available but can be brittle under missing or corrupted modalities.Self-Other Neural Representational Distinction is Associated with Distorted Social Predictions in Social Anxiety
Social anxiety (SA) is characterized by distorted negative expectations about the future.Computational Analysis of Antioxidant Effects on Stress Response Mechanisms in Candida albicans
Candida albicans was used as a eukaryotic model to study aging and oxidative stress response pathways focused on NAD dependent deacetylases, Sir2 and SIRT3.Decision benchmarking of cryo-EM re-refinement
Map fit is widely used in cryo-EM re-refinement.Reference-Guided De Novo Retrieval of 3D Chromatin Organizational Features with Representation Learning
Chromosome conformation maps reveal spatial genome organization through recurring contact patterns, some associated with established architectural features and others with less understood biological…Top2All: Benchmarking sparse-to-transcriptome reconstruction from high-expression profiles across sex- and sex-steroid-defined conditions
Transcriptome-wide profiling at single-cell resolution is limited by sparse detection of gene expression, raising the question of how much transcriptomic information can be recovered from a small…Thalamic stereo-EEG detects sleep stages N2 and N3 with discrimination approaching scalp EEG
Sleep and epilepsy interact strongly during sleep stages N2 and N3, when synchronization of brain rhythms is increased.SQANTI-evidence: isoform-resolved, evidence-tiered structural annotation of unannotated genomes from long-read RNA-seq
Long-read RNA sequencing captures full-length transcripts, yet current annotation pipelines fail to properly curate the data for gene prediction.The Segmentome: a novel representation of the DNA methylome identified by a Bayesian HMM framework
DNA methylation is organized along the genome into regions of relatively stable methylation (i.e. fully methylated or fully unmethylated regions), separated by transition zones.An end-to-end in silico framework for truth-based validation and regression testing of clinical genome sequencing pipelines, from simulated reads to reportable findings
Clinical genome sequencing pipelines change often, and each change requires proportionate revalidation.
Get the few papers worth your time in Life Sciences every morning.
Choose your topics and ReadSearch reads the new papers in them each day, then brings you the few worth reading, each with its key finding in a sentence.